CENTER PUBLICATIONS

Publications prepared during the past four years since the onset of the current grant cycle in 1996 are listed next in alphabetical order. Publications are listed in the Progress Report for individual MRRC investigators (see Section B), according to the author's primary affiliation in one of the four MRRC programs, i.e., Genetics, Developmental Biology, Basic Neuroscience, and Clinical Neuroscience/Behavior.

Zafft, C.; Hart, D.; Zimbrich, K.; Kiernan, W., College Career Connection: a study of youth with intellectual disabilites and the impact of postsecondary education, Education and Training in Developmental Disabilities , 2004, 39(1), 45-53

Zakaria, M.; Dunn, I.C.; Smith, E.; Su, E.; Patriquin, E.; Radovick, S., Phorbol ester regulation of the gonadotropin-releasing hormone gene in a GnRH- secreting call line: the modular basis of species differences, Mol. Endocrinol. , 1996, 10, 1282-1291

Zaknun, D.; Orav, J.; Kornegay, J.; al-Attar, I.; Fuchs, D.; Zaknun, J.; Wachter, H.; Chatis, P.; Burchett, S.K.; McIntosh, K., Correlation of ribonucleic acid polymerase chain reaction, acid dissociated p24 antigen, and neopterin with progression of disease. A retrospective, longitudinal study of vertically acquired human immunodeficiency virus type 1 infection in children, J. Pediatr. , 1997, 130, 898-905

Zaknun, D.; Zangerle, R.; Kapelari, K.; Fischer, H.; Sailer, M.; McIntosh, K., Concurrent ganciclovir and foscarnet treatment for cytomegalovirus encephalitis and retinitis in an infant with acquired immunodeficiency syndrome: case report and review, Pediatr. Infect. Dis. J. , 1997, 16, 807-11

Zamani, A.A.; Moriarty, T.; Hsu, L.; Winalski, C.S.; Schaffer, J.L.; Isbister, H.; Schenck, J.F.; Rohling, K.W.; Jolesz, F., Functional MRI of the lumbar spine in erect position in a superconducting open- configuration MR system: preliminary results, J. Magn. Reson. Imaging , 1998, 8, 1306-1318

Zanger, K.; Cohen, L.E.; Hashimoto, K.; Radovick, S.; Wondisford, F.E., A novel mechanism for cyclic adenosine 3\', 5\'-monophosphate regulation of gene expression by CREB-binding protein, Mol. Endocrinol. , 1999, 13, 268-275

Zappaterra MD LS, Lindsay S, Gygi SP, Walsh CA, Ballif BA, A Comparative Proteomic Analysis of Human and Rat Embryonic Cerebospinal Fluid, Journal of Proteome Research , 2007, , pubmed

Zareba, W.; Moss, A.J.; Sheu, G.; Kaufman, E.S.; Priori, S.; Vincent, G.M.; Towbin, J.A.; Benhorin, J.; Schwartz, P.J. Napolitano, C.; Hall, W.J.; Keating, M.T.; Qi, M.; Robinson, J.L.; Andrews, M.L., Location of mutation in the KCNQ1 and phenotypic presentation of long QT syndrome., J. Cardiovasc. Electrophysiol. , 2003, 14(11), 1149-53 pubmed

Zaritsky, J.J.; Eckman, D.M.; Wellman, G.C.; Nelson, M.T.; Schwarz, T.L., Targeted disruption of Kir2.1 and Kir2.2 genes reveals the essential role of the inwardly rectifying K(+) current in K(+)-mediated vasodilation., Circ. Res. , 2000 , 87(2), 160-6 pubmed

Zaritsky, J.J.; Redell, J.B.; Tempel, B.L.; Schwarz, T.L., The consequences of disrupting cardiac inwardly rectifying K(+) current (I(K1)) as revealed by the targeted deletion of the murine Kir2.1 and Kir2.2 genes., J. Physiol. , 2001 , 533(Pt 3), 697-710 pubmed

Zeanah C, Smyke A, Koga S, Carlson E, group atBc, Attachment in institutionalized and community children in Romania, Child Development , 2005, 76, 1015-28 pubmed

Zec, N.; Filiano, J.J.; Kinney, H.C., Anatomic relationships of the human arcuate nucleus of the medulla: a DiI-labeling study, J. Neuropath. Exp. Neurol. , 1997, 56, 509-22

Zec, N.; Filiano, J.J.; Panigraphy, A.; White, W.F.; Kinney, H.C., Developmental changes in [3H]-lysergic acid diethylamide ([3H]LSD) binding to serotonin receptors in the human brainstem, J. Neuropathol. Exp. Neurol. , 1996, 55, 114-126

Zec, N.; Kinney, H.C., Anatomic relationships of the human nucleus paragigantocellularis lateralis. A DiI labeling study, Auto. Neurosci. , 2001, 89, 110-124 pubmed

Zec, N.; Kinney, H.C., Anatomic relationships of the human nucleus of the solitary tract: A Dil labeling study, Auto. Neurosci. , 2003, 105, 131-144

Zec, N.; Kinney, H.C., Dil labeling studies in the medulla oblongata of the human fetus: Relevance to the sudden infant death syndrome, Brain Res. Rev. , 2005, , (under revision)

Zec, N.; Rowitch, D.H.; Bitgood, M.J.; Kinney, H.C., Expression of the homeobox-containing genes EN1 and EN2 in human fetal midgestational medulla and cerebellum, J. Neuropath. Exp. Neurol. , 1997, 56, 236-42

Zeng, W.; Silverman, G.A.; Remold-O-Donnell, E., Structure and sequence of human M/NEI (monocyte/neutrophil elastase inhibitor), an Ov-serpin family gene, Gene , 1998, 213, 179-187

Zent, R.; Bush, K.T.; Pohl, M.L.; Quaranta, V.; Koshikawa, N.; Wang, Z.; Kreidberg, J.A.; Sakurai, H.; Stuart, R.O.; Nigam, S.K., Involvement of laminin binding integrins and Laminin-5 in branching morphogenesis of the ureteric bud during kidney development, Developmental Biology , 2001, 238, 289-302 pubmed

Zervos, A.; Hunt, K.E.; Tong, H.Q.; Avallone, J.; Morales, J.; Friedman, N.; Cohen, B.H.; Clark, B.; Guo, S.; Gazda, H.; Beggs, A.H.; Traboulsi, E.I., Clinical, genetic and histopathologic findings in two siblings with muscle-eye-brain disease, Eur. J. Ophthalmol. , 2002, 12, 253-61 pubmed

Zetsche B, Dai D, Brown JR, Kanner C, Jackson-Grusby L, Single-copy conditional RNAi transgenesis in ES cells and mice, , , Submitted,

Zhang W, Chen X, Kato Y, Evans PM, Yuan S, Yang J, Rychahou PG, Yang VW, He X, Evers BM, Liu C, Novel cross talk of Kruppel-like factor 4 and beta-catenin regulates normal intestinal homeostasis and tumor repression, Mol Cell Biol , 2006, 26(6):2055-64, pubmed

Zhang W.;Chen X., Kato Y.; Evans PM.;Yuan S., Yang J.; Rychahou PG.;Yang VW.;He X.; Evers BM.; Liu CM., Novel crosstalk of KLF and eta-cantenin regulates normal intestinal hoeostasis and tumor repression, Mol. Cell Biology , 2006, 26, 2055-2064

Zhang Y, Aizenman E, DeFranco DB, Rosenberg PA, Intracellular zinc release, 12-lipoxygenase activation and MAPK dependent neuronal and oligodendroglial death, Mol Med , 2007, 13(7-8), 350-5 pubmed

Zhang, H.; Palmer, R.; Gao, X.; Kreidberg, J.; Gerald, W.; Hsiao, L.; Jensen, R.V.; Gullans, S.R.; Haber, D.A., Transcriptional activation of placental growth factor by the forkhead/winged helix transcription factor FoxD1., Curr. Biol. , 2003 , 13 (18), 1625-9 pubmed

Zhang, H.H.; Lipovsky, A.I.; Dibble, C.C.; Sahin, M.; Mannaing, B.D., S6K1 Regulates GSK3 under Conditions of mTOR-Dependent Feedback Inhibition of Akt, Molecular Cell , 2006, 24, 185-97

Zhang, J.; Gray, J.; Wu, L.; Leone, G.; Rowan, S.; Cepko, C.L.; Zhu, X.; Craft, C,M,; Dyer, M.A., Rb regulates proliferation and rod photoreceptor development in the mouse retina, Nat. Genet. , 2004, 36, 351-360 pubmed

Zhang, L.; Timothy, K.W.; Vincent, G.M.; Lehmann, M.H.; Fox, J.; Giuli, L.C.; Shen, J.; Splawski, I.; Priori, S.G.; Compton, S.J.; Yanowitz, F.; Benhorin, J.; Moss, A.J.; Schwartz, P.J.; Robinson, J.L.; Wang, Q.; Zareba, W.; Keating, M.T.; Towbin, J.A.; Napolitano, C.; Medina, A., Spectrum of ST-T-wave patterns and repolarization parameters in congenital long-QT syndrome: ECG findings identify genotypes., Circulation , 2000 , 102(23), 2849-55 pubmed

Zhang, L.; Vincent, G.M.; Baralle, M.; Baralle, F.E.; Anson, B.D.; Benson, D.W.; Whiting, B.; Timothy, K.W.; Carlquist, J.; January, C.T.; Keating, M.T.; Splawski, I., An intronic mutation causes long QT syndrome., J. Am. Coll. Cardiol. , 2004 , 44(6), 1283-91 pubmed

Zhang, X.; He, X.; Fu, XY.;Chang, ZJ., Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics, Cell Sci , 2006, 119, 1053-1062 pubmed

Zhang, Y.; Qiu, W.J.; Chan, S.C.; Han, J.H.; He, X.; Lin, S.C., Casein kinase I and casein kinase II differentially regulate axin function in Wnt and JNK pathways, J. Biol. Chem. , 2002, 277, 17706-17712

Zhang, Y.; Rosenberg, P.A., The essential nutrient pyrroloquinoline quinone may act as a neuroprotectant by suppressing peroxynitrite formation, Eur. J. Neurosci. , 2002, 16(6), 1015-24 pubmed

Zhang, Y.; Rosenberg, P.A., Caspase-1 and poly (ADP-ribose) polymerase inhibitors may protect against peroxynitrite-induced neurotoxicity independent of their enzyme inhibitor activity., Eur. J. Neurosci. , 2004 , 20(7), 1727-36 pubmed

Zhang, Y.; Wang, H.; Li, J.; Dong, L.; Volpe, J.J.; Rosenberg, P.A., Intracellular zinc release and extracellular signal receptor kinase phosphorylation are required upstream of 12-lipoxygenase activation in peroxynitrate toxicity to mature rat oligodendrocytes, J Biol Chem , 2006, 281, 9460-70 pubmed

Zhang, Y.; Wang, H.; Li, J.; Jimenez, D.A.; Levitan, E.S.; Aizenman, E.; Rosenberg, P.A., Peroxynitrite-induced neuronal apoptosis is mediated by intracellular zinc release and 12-lipoxygenase activation., J. Neurosci. , 2004 , 24(47), 10616-27 pubmed

Zhang, Z.; Hartmann, H.; Do, V.M.; Abramowski, D.; Sturchler-Pierrat, C.; Staufenbiel, M.; Sommer, B.; van de Wetering, M.; Clevers, H.; Saftig, P.; De Strooper, B.; He, X.; Yankner, B.A., Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis, Nature , 1998, 395, 698-702

Zhang, Z.; Nadeau, P.; Song, W.; Donoviel, D.; Yuan, M.; Bernstein, A.; Yankner, B.A., Presenilins are required for gamma-secretase cleavage of beta-APP and transmembrane cleavage of Notch-1, Nat. Cell Biol. , 2000, 2, 463-5 pubmed

Zhao Q, Shao J, Chen W, Li YP, Osteoclast differentiation and gene regulation, Front Biosci , 2007, 12, 2519-29 pubmed

Zhao W, Kitidis C, Fleming M, Lodish H, Ghaffari S, Erythropoietin stimulates phosphorylation and activation of GATA-1 via the PI3-kinase-AKT signaling pathway, Blood , 2006, 107(3), 907-15 pubmed

Zhao WN, Malinin N, Yang FC, Staknis D, Gekakis N, Maier B, Reischl S, Kramer A, Weitz CJ, CIPC is a mammalian circadian clock protein without invertebrate homologues, Nat Cell Biol , 2007, 9(3), 268-75 pubmed

Zhao, L.; Mulkern, R.; Tseng, C.H.; Williamson, D.; Patz, S.; Kraft, R.; Walsworth, R.L.; Jolesz, F.A.; Albert, M.S., Gradient-Echo Imaging Considerations for Hyperpolarized 129Xe MR, J. Magn. Reson. B. , 1996, 113, 179-83

Zhao, Q.; Kho, A.; Kenney, A.M.; Yuk Di, D.I.; Kohane, I.; Rowitch, D.H., Identification of genes expressed with temporal-spatial restriction to developing cerebellar neuron precursors by a functional genomic approach, Proc. Natl. Acad. Sci. U .S .A. , 2002, 99, 5704-9 pubmed

Zhdanova, I.V.; Wurtman, R.J.; Wagstaff, J., Effects of a low dose of melatonin on sleep in children with Angelman syndrome, J. Pediatr. Endocrinol. Metabol. , 1999, 12, 57-67

Zhen, S.; Dunn, I.C.; Wray, S.; Liu, Y.; Chappell, P.E.; Levine, J.E.; Radovick, S., An alternative splicing product found in cultured GnRH neurons and mouse hypothalamus, J. Biol. Chem. , 1997, 272, 12620-12625

Zhen, S.; Zakaria, M.; Wolfe, A.; Radovick, S., Regulation of gonaotropin-releasing hormone (GnRH) gene expression by insulin- like growth factor 1 in a cultured GnRH- expressing neuronal line, Mol. Endocrinol. , 1997, 11, 1145-1155

Zhou B, Ma Q, Rajagopal S, Wu SM, Domian I, Rivera-Feliciano J, Jiang D, von Gise A, Ikeda S, Chien KR, Pu WT, Epicardial-derived Wt1+ progenitors contribute to the cardiomyocyte lineage in the developing heart, Nature , 2008, Under review,

Zhou P, Porcionatto M, Pilapil M, Chen Y, Choi Y, Tolias KF, Bikoff JB, Hong EJ, Greenberg ME, Segal RA, Polarized signaling endosomes coordinate BDNF-induced chemotaxis of cerebellar precursors, Neuron , 2007, 55(1), 53-68 pubmed

Zhou Z, Hong E, Cohen S, Zhao W, Ho H, Schmidt L, Chen W, Savner E, Griffith E, Hu L, Steen J, Weitz C, Greenberg M, Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation, Neuron , 2006, 52, 255-69 pubmed

Zhou, J.; Liyanage, U.; Medina, M.; Ho, C.; Simmons, A.D.; Lovett, M.; Kosik, K.S., Presenilin 1 interaction in the brain with a novel member of the Armadillo family, Neuroreport , 1997, 8, 1489-94

Zhuang, Z.Y.; Xu, H.; Clapham, D.E.; Ji, R.R., Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization., J. Neurosci. , 2004, 24(38), 8300-8309 pubmed

Zientara, G.P.; Panych, L.P.; Jolesz, F.A., Applicability and efficiency of near-optimal spatial encoding for dynamically adaptive MRI, Magn. Reson. Med. , 1998, 39, 204-13

Zientara, G.P.; Saiviroonporn, P.; Morrison, P.R.; Fried, M.P.; Hushek, S.G.; Kikinis, R.; Jolesz, F.A., MRI monitoring of laser ablation using optical flow, J. Magn. Reson. Imaging , 1998, 8, 1306-1318

Zimmerman MA, Goumnerova LC, Proctor M, Scott RM, Marcus K, Pomeroy SL, Turner CD, Chi SN, Chordas C, Kieran MW, Continuous remission of newly diagnosed and relapsed central nervous system atypical teratoid/rhabdoid tumor, J Neurooncol , 2005, 1, 77-84

Zollino, M.; Colosimo, C.; Zuffardi, O.; Rossi, E.; Tosolini, A.; Walsh, C.A.; Neri, G., Cryptic t(1;12)(q44;p13.3) translocation in a previously described syndrome with polymicrogyria, segregating as an apparently X-linked trait, Am. J. Med. Genet. , 2003, 117, 65-71

Zurakowski, D.; Di Canzio, J.; Majzoub, J.A., Pediatric reference intervals for serum thyroxine, triiodothyronine, thyrotropin, and free thyroxine, Clinical Chemistry , 1999, 45, 1087-91