CENTER PUBLICATIONS

Publications prepared during the past four years since the onset of the current grant cycle in 1996 are listed next in alphabetical order. Publications are listed in the Progress Report for individual MRRC investigators (see Section B), according to the author's primary affiliation in one of the four MRRC programs, i.e., Genetics, Developmental Biology, Basic Neuroscience, and Clinical Neuroscience/Behavior.

LaBonne, C.;Whitman, M., Localization of MAP kinase activity in early Xenopus embryos: implications for endogenous FGF signaling, Dev Biol , 1997, 183, 20-Sep

Lacorazza, H. D.;Flax, J. D.;Snyder, E. Y.;Jendoubi, M., Expression of human beta-hexosaminidase alpha-subunit gene (the gene defect of Tay-Sachs disease) in mouse brains upon engraftment of transduced progenitor cells, Nature Medicine , 1996, 2, 424-9

Lacy, S. E.;Bonnemann, C. G.;Buzney, E. A.;Kunkel, L. M., Identification of FLRT1, FLRT2, and FLRT3: a novel family of transmembrane leucine-rich repeat proteins, Genomics , 1999, 62, 417-426

Lader AS, Ramoni MF, Zetter BR, Kohane IS, Kwiatkowski DJ., Identification of a transcriptional profile associated with in vitro invasion in non-small cell lung cancer cell lines., Cancer Biol Ther. , 2004 , 3(7), 624-31 pubmed

Lagutin, O.;Zhu, c C.;Furuta, Y.;Rowitch, D. H.;McMahon, a P.;Oliver, G., Six3 promotes the formation of ectopic optic vesicles in mouse embryos, Dev Dynamics , 2001, 221, 342-349

Lalande, M., Parental imprinting and human disease, Ann. Rev. Genet. , 1996, 30, 173-95

Lallemant, M.;McIntosh, K.;Jourdain, G.;Le Coeur, S.;Vithayasai, V.;Lee, T. H.;Hammer, S.;Prescott, N.;Essex, M., Ethics of placebo-controlled trials of zidovudine to prevent the perinatal transmission of HIV in the Third World, N Eng. J. Med , 1998, 338, 839-40

Lambers T, Mahieu F, Oancea E, Hoofd L, de Lange F, Mensenkamp A, Voets T, Nilius B, Clapham D, Hoenderop J, Bindels R, Calbindin-D28K dynamically controls TRPV5-mediated Ca2+ transport, EMBO J , 2006, 25, 2978-88 pubmed

Landesman, Y.;Sokol, S., Xwnt-2b is a novel axis-inducing Xenopus Wnt, which is expressed in embryonic brain, Mech. Dev. , 1997, 63, 199-209

Landisman, C. E.;Long, M. E.;Beierlein, M.;Deans, M. R.;Paul, D. L.;Connors, B. W., Electrical synapses in the thalamic reticular nucleus, J Neurosci , 2002, 22, 1002-1009 pubmed

Landsberg R, Awatramani RB, Hunter N, Farago A, DiPietrantoio H, Dymecki S, Hindbrain Rhombic Lip is Comprised of Discrete Progenitor Cell Populations Allocated by Pax6, Neuron , 2005, 48, 933-47 pubmed

Langenau DM, Keefe MD, Storer NY, Guyon JR, Kutok JL, Le X, Goessling W, Neuberg DS, Kunkel LM, Zon LI, Effects of RAS on the genesis of embryonal rhabdomyosarcoma, Genes Dev , 2007, 21(11), 1382-95 pubmed

Langevin J, Morgan MJ, Sibarita JB, Aresta S, Murthy M, Schwarz T, Camonis J, Bellaiche Y, Drosophila exocyst componenets Sec5, Sec5, and Sec15, regulate Decadherin trafficking from recycling endosomes to the plasma membrane, Dev Cell , 2005, 9, 355-76

Lanier, L. M.;Gates, M. A.;Witke, W.;Menzies, A. S.;Wehman, A. M.;Macklis, J. D.;Kwiatkowski, D.;Soriano, P.;Gertler, F. B., Mena is required for neurulation and commissure formation, Neuron , 1999, 22, 313-25

Lanphear, B. P.;Vorhees, C. V.;Bellinger, D. C., Protecting children from environmental toxins - Toxicity testing of pesticides and industrial chemicals is a crucial step - art. no. e61, Plos Medicine , 2005, 2, 203-208

Lanphear, B.P.; Hornung, R.; Khoury, J.; Yolton, K.; Baghurstl, P.; Bellinger, D.C.; Canfield, R.L.; Dietrich, K.N.; Bornschein, R.; Greene, T.; Rothenberg, S.J.; Needleman, H.L.; Schnaas, L.; Wasserman, G.; Graziano, J. and Roberts, R., Low- level environmental lead exposure and children\'s intellectual function: An international pooled analysis, Environmental Health Perspectives , 2005, 113, 894- 899 pubmed

LaSalle, J. M.;Lalande, M., Homologous association of oppositely imprinted chromosomal domains, Science , 1996, 272, 725-8

LaSalle, J. M.;Ritchie, R. J.;Glatt, H.;Lalande, M., Clonal heterogeneity at allelic methylation sites diagnostic for Prader-Willi and Angelman syndromes, PNAS USA , 1998, 95, 1675-80

Laughon M, Bose C, Allred E, O'Shea TM, Van Marter LJ, Bednarek F, Leviton A, Factors associated with treatment for hypotension in extremely low gestational age newborns during the first postnatal week, Pediatrics , 2007, 119(2), 273-80 pubmed

Laura, R. P.;Witt, A. S.;Held, H. A.;Gerstner, R.;Deshayes, K.;Koehler, M. F. T.;Kosik, K. S.;Sidhu, S. S.;Lasky, L. A., The Erbin PDZ domain binds with high affinity and specificity to the carboxyl termini of d-catenin and ARVCF, J Biological Chem , 2002, 277, 12906-12914

Laxmanan S, Datta D, Geehan C, Briscoe D, Pal S, CD40: A mediator of pro- and anti-inflammatory signals in renal tubular epithelial cells, J Am Soc Nephrol , 2005, 9, 2714-23 pubmed

Laxmanan S, Robertson S, Wang E, Lau J, Briscoe D, Mukhopadhyay D, Vascular endothelial growth factor impairs the functional ability of dendritic cells through Id pathways, Biochem Biophys Res Comm , 2005, 334(1), 193-8 pubmed

Löfqvist C, Andersson E, Sigurdsson J, Engström E, Hård A-L, Niklasson A, Smith L, Hellström A, Longitudinal postnatal weight and IGF-I measurements improve prediction of ROP, Archives of Ophthalmology , 2006, 124(12), 1711-8 pubmed

Löfqvist C, Egström E, Sigurdsson J, Hård A-L, Niklasson A, Ewald U, Holmström G, Smith L, Hellström A, Postnatal head growth deficit in premature infants parallels retinopathy of prematurity and IGF-1 deficit, Pediatrics , 2006, 117(6), 1930-8 pubmed

Le M, Lu Y, Li Y, Greene RW, Epstein PM, Rosenberg PA., Zaprinast stimulates extracellular adenosine accumulation in rat pontine slices., Neurosci Lett. , 2004 , 371(1), 12-7

Le, P. P.;Kohane, I. S.;Weeks, J. C., Using a pen-based computer to collect health-related quality of life and utilities information, Proc Annu Symp Comput Appl Med Care , 1995, , 839-43 pubmed

Leavitt, B. R.;Hernit-Grant, C. S.;Macklis, J. D., Mature astrocytes transform into transitional radial glia within adult mouse neocortex that supports directed migration of transplanted immature neurons, Exper Neurol , 1999, 157, 43-57

Lechpammer M, Manning SM, Samonte F, Nelligan J, Sabo E, Talos DM, Volpe JJ, Jensen FE, Minocycline treatment following hypoxic/ischaemic injury attentuates white matter injury in a rodent model of periventicular leucomalacia, Neuorpathol Appl Neurobiol , , ,

Leclerc, N.;Baas, P. W.;Garner, C. C.;Kosik, K. S., Juvenile and mature MAP2 isoforms induce distinct patterns of process outgrowth, Molec Biol Cell , 1996, 7, 443-55

Lee SA, Haiman CA, Burtt NP, Pooler LC, Cheng I, Kolonel LN, Pike MC, Altshuler D, Hirschhorn JN, Henderson BE, Stram DO, A comprehensive analysis of common genetic variation in prolactin (PRL) and PRL receptor (PRLR) genes in relation to plasma prolactin levels and breast cancer risk: the multiethnic cohort, BMC Med Genet , 2007, 8, 72 pubmed

Lee, B. H.;Scharff, L.;Sethna, N. F.;McCarthy, C. F.;Scott-Sutherland, J.;Shea, A. M.;Sullivan, P.;Meier, P.;Zurakowski, D.;Masek, B. J.;Berde, C. B., Physical therapy and cognitive-behavioral treatment for complex regional pain syndromes, J Pediatr , 2002, 141, 135-140 pubmed

Lee, C. U.;Shenton, M. E.;Salisbury, D. F.;Kasai, K.;Onitsuka, T.;Dickey, C. C.;Yurgelun-Todd, D.;Kikinis, R.;Jolesz, F. A.;McCarley, R. W., Fusiform gyrus volume reduction in first-episode schizophrenia: a magnetic resonance imaging study, Arch Gen Psychiatry , 2002, 59, 755-781

Lee, K. H.;Cotanche, D. A., Potential role of bFGF and retinoic acid in the regeneration of chicken cochlear hair cells, Hearing Research , 1996, 94, 13-Jan

Lee, K. H.;Cotanche, D. A., Localization of the hair cell specific portein fimbrin during regeneration in the chicken cochlea, Audiol Neuro-Otolog , 1996, 2, 61-70

Lee, K.;Kohane, I. S.;Butte, A. J., PGAGENE: integrating quantitative gene-specific results from the NHLBI Programs for Genomic Applications, Bioinformatics , 2003, 19, 778-9 pubmed

Lee, P.;Goish, K.;Davidson, A. J.;Mannix, R.;Zon, L.;Klagsbrun, M., Neuropilin-1 is required for vascular development and is a mediator of VEGF-dependent angiogenesis in zebrafish, PNAS USA , 2002, 99, 10470-10475 pubmed

Lee, S. J.;Liyanage, U.;Bickel, P. E.;Xia, W.;Lansbury, P. T., Jr.;Kosik, K. S., A detergent-insoluble membrane compartment contains A beta in vivo, Nature Medicine , 1998, 4, 730-4

Lehnardt S, Massillon L, Follett P, Jensen FE, Ratan R, Rosenberg PA, Volpe JJ, Vartanian T., Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway., Proc Natl Acad Sci U S A. , 2003 , 100(14), 8514-9 pubmed

Lehnardt, S.;Lachance, C.;Patrizi, S.;Lefebvre, S.;Follett, P. L.;Jensen, F. E.;Rosenberg, P. A.;Volpe, J. J.;Vartanian, T., The toll-like receptor TLR4 is necessary for lipopolysaccharide-induced oligodendrocyte injury in the CNS, J Neurosci , 2002, 22, 2478-2486 pubmed

Lehoczky J, Cai W-W, Douglas J, Moran J, Beier D, Innis J, Description and genetic mapping of Polypodia: an X-linked dominant mouse mutant with ectopic caudal limbs and other malformations, Mammalian Genome , 2006, 17, 903-13 pubmed

Lein ES, Shatz CJ., Rapid regulation of brain-derived neurotrophic factor mRNA within eye-specific circuits during ocular dominance column formation., J Neurosci. , 2000 , 20(4), 1470-83 pubmed

Lein, E. S.;Shatz, C. J., Neurotrophins and refinement of visual circuitry, Synapses , 2001, , 613-649.

Lemere, C. A.;Lopera, F.;Kosik, K. S.;Lendon, C. L.;Ossa, J.;Saido, T. C.;Yamaguchi, H.;Ruiz, A.;Martinez, A.;Madrigal, L.;Hincapie, L.;Arango, J. C.;Anthony, D. C.;Koo, E. H.;Goate, A. M.;Selkoe, D. J., The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology, Nature Medicine , 1996, 2, 1146-50

Lendon, C. L.;Martinez, A.;Behrens, I. M.;Kosik, K. S.;Madrigal, L.;Norton, J.;Neuman, R.;Myers, A.;Busfield, F.;Wragg, M.;Arcos, M.;Arango Viana, J. C.;Ossa, J.;Ruiz, A.;Goate, A. M.;Lopera, F., E280A PS-1 mutation causes Alzheimer's disease but age of onset is not modified by ApoE alleles, Human Mutation , 1997, 10, 186-95

Leon, S.;Yin, Y.;Nguyen, J.;Irwin, N.;Benowitz, L. I., Lens injury stimulates axon regeneration in the mature rat optic nerve, J. Neurosci , 2000, 20, 4615-4626 pubmed

Leppanen JM, Moulson MC, Vogel-Farley VK, Nelson CA, An ERP study of emotional face processing in the adult and infant brain, Child Dev , 2007, 78(1), 232-45 pubmed

Lester, B. M.;Lagasse, L.;Seifer, R.;Tronick, E. Z.;Bauer, C. R.;Shankaran, S.;Bada, H. S.;Wright, L. L.;Smeriglio, V. L.;Liu, J.;Finnegan, L. P.;Maza, P. L., The Maternal Lifestyle Study (MLS): effects of prenatal cocaine and/or opiate exposure on auditory brain response at one month, J Pediatr , 2003, 142, 279-85 pubmed

Lester, B. M.;Tronick, E. Z.;LaGasse, L.;Seifer, R.;Bauer, C. R.;Shankaran, S.;Bada, H. S.;Wright, L. L.;Smeriglio, V. L.;Lu, J.;Finnegan, L. P.;Maza, P. L., The maternal lifestyle study: effects of substance exposure during pregnancy on neurodevelopmental outcome in 1-month-old infants, Pediatrics , 2002, 110, 1182-92 pubmed

Leviton A, The discourteous reviewer, Paediatr Perinat Epidemiol , 2007, 21(1), 2-4 pubmed

Leviton A, Motivated reasoning, Acta Paediatr , 2007, 96(7), 949 pubmed

Leviton A, Blair E, Dammann O, Allred E, The wealth of information conveyed by gestational age, J Pediatr , 2005, 1, 123-7 pubmed

Leviton A, Dammann O, Durum S, The adaptive immune response in neonatal cerebral white matter damage, Ann Neurol , 2005, 58, 821-8 pubmed

Leviton A, Gressens P, Neuronal damage accompanies perinatal white-matter damage, Trends Neurosci , 2007, 30(9), 473-8 pubmed

Leviton, A., Kuban, L., Paneth, N., Intraventricular haemorrhage grading scheme: time to abandon, Acta Paediatrica , 2007, ,

Leviton, A., Kuban, L., Paneth, N., Intraventricular haemorrhage grading scheme: time to abandon, Acta Paediatrica , 2007, ,

Leviton, A., Kuban, L., Paneth, N., Intraventricular haemorrhage grading scheme: time to abandon, Acta Paediatrica , 2007, ,

Leviton, A., Kuban, L., Paneth, N., Intraventricular haemorrhage grading scheme: time to abandon, Acta Paediatrica , 2007, ,

Leviton, A.;Dammann, O., Brain damage markers in children. Neurobiological and clinical aspects, Acta Paediatr , 2002, 91, 13-Sep

Leviton, A.;Dammann, O.;Allred, E. N.;Kuban, K. C.;Pagano, M.;Van Marter, L. J.;Paneth, N.;Reuss, M. L.;Susser, M. for The Developmental Epidemiology Network, Antenatal corticosteroids and cranial ultrasound abnormalities, AJOG , 1999, 181, 1007-1017

Leviton, A.;Dammann, O.;O\'Shea, T. M.;Paneth, N., Adult stroke and perinatal brain damage: like grandparent, like grandchild?, Neuropediatrics , 2002, 33, 281-287 pubmed

Leviton, A.;Gilles, F., Ventriculomegaly, delayed myelination, white matter hypoplasia, and "periventricular" leukomalacia: how are they related?, Pediatr. Neurol. , 1996, 15, 127-136

Leviton, A.;Holmes, L. B.;Allred, E. N.;Vargas, J. E., Methodologic issues in epidemiologic studies of congenital microcephaly, Early Human Development , 2002, 69, 91-105

Leviton, A.;Paneth, N.;Reuss, M. L.;Susser, M.;Allred, E. N.;Dammann, O.;Kuban, K.;Van Marter, L. J.;Pagano, M., Maternal infection, fetal inflammatory response, and brain damage in very low birthweight infants, Pediatr. Res. , 1999, 46, 566-575

Leviton, A.;Paneth, N.;Reuss, M. L.;Susser, M.;Allred, E. N.;Dammann, O.;Kuban, K.;Van Marter, L. J.;Pagano, M. for The Developmental Epidemiology Network Investigators, Hypothyroxinemia of prematurity and the risk of cerebral white matter damage, J Pediatr , 1999, 134, 706-711

Leviton, A.;Paneth, N.;Susser, M.;Reuss, M. L.;Allred, E. N.;Kuban, K.;Sanocka, U.;Hegyi, T.;Hiatt, M.;Shahrivar, F.;Van Marter, L. J., Maternal receipt of magnesium sulfate does not seem to reduce the risk of neonatal white matter damage, Pediatrics , 1997, 99, E2

Levitt, J. J.;McCarley, R. W.;Dickey, C. C.;Voglmaier, M. M.;Niznikiewicz, M. A.;Seidman, L. J.;Hirayasu, Y.;Ciszewski, A. A.;Kikinis, R.;Jolesz, F. A.;Shenton, M. E., MRI study of caudate nucleus volume and its cognitive correlates in neuroleptic-naive patients with schizotypal personality disorder, Am J Psychiatry , 2002, 159, 1190-1197

Levitt, J. J.;McCarley, R. W.;Nestor, P. G.;Petrescu, C.;Donnino, R.;Hirayasu, Y.;Kikinis, R.;Jolesz, F. A.;Shenton, M. E., Quantitative volumetric MRI study of the cerebellum and vermis in schizophrenia: clinical and cognitive correlates, Am J Psychiatry , 1999, 156, 1105-7

Levy HL MA, Chakrapani A, Cleary M, Lee P, Trefz FK, Whitley CB, Feillet F, Feigenbaum AS, et al, Efficacy of sapropterin dihydrochloride (tetrahydrobiopterin, 6R-BH4) for reduction of phenylalanine concentration in patients with phenylketonuria: a phase III randomised placebo-controlled study., Lancet , 2007, 370, 504-10 pubmed

Levy, H., Nasogastric and nasoenteric feeding tubes, Gastrointest. Endoscop Clin NA , 1998, 8, 529-49

Levy, H. L., Reproductive effects of maternal metabolic disorders: implications for pediatrics and obstetrics, Turkish J. Pediatr. , 1996, 38, 335-344

Levy, H. L., Long-term follow-up of maternal phenylketonuria: an international study, Genetic Disorders and Pregnancy Outcome , 1997, , 33-40

Levy, H. L., Newborn screening by tandem mass spectrometry: A new era, Clin. Chem. , 1998, 44, 2401-2402

Levy, H. L., Increasing brain tyrosine in treated phenylketonuria, J. Inher. Metab. Dis. , 1998, 21, May-52

Levy, H. L., Phenylketonuria: old disease, new approach to treatment, PNAS USA , 1999, 96, 1811-18113

Levy, H. L., Hartnup disorder, The Metabolic and Molecular Bases of Inherited Disease , 2001, , 4957-4969

Levy, H. L.;Albers, S., Genetic screening of newborns, Annu Rev Genomics Hum Genet , 2000, 1, 139-77 pubmed

Levy, H. L.;Brown, A. E.;Williams, S. E.;de Juan, E., Vitreous hemorrhage as an ophthalmic complication of galactosemia, J. Pediatr. , 1996, 129, 922-925

Levy, H. L.;Ghavami, M., Maternal phenylketonuria: a metabolic teratogen, Teratology , 1996, 53, 176-184

Levy, H. L.;Guldberg, P.;Guttler, F.;Hanley, W. B.;Matalon, R.;Rouse, B. M.;Trefz, F.;Azen, C.;Allred, E. N.;de la Cruz, F.;Koch, R., Congenital heart disease in maternal phenylketonuria: Report from the Maternal PKU Collaborative Study, Pediatr Res , 2001, 49, 636-642

Levy, H. L.;Lobbregt, D.;Platt, L. D.;Benacerraf, B. R., Fetal ultrasonography in maternal PKU, Prenat Diagn , 1996, 16, 599-604

Levy, H. L.;Taylor, R. G.;McInnes, R. R., Disorders of histidine metabolism, The Metabolic and Molecular Bases of Inherited Disease , 2001, , 1807-1820

Levy, H. L.;Waisbren, S. E.;Lobbregt, D.;Allred, E.;Leviton, A.;Koch, R.;Hanley, W. B.;Rouse, B.;Matalon, R.;de la Cruz, F., Maternal non-phenylketonuric mild hyperphenylalaninemia, Eur J Pediatr , 1996, 155 Suppl 1, S20-S25

Levy, H.;Ash, S. R.;Knab, W.;Steczko, J.;Carr, D. J.;Blake, D. E., Systemic inflammatory response syndrome treatment by powdered sorbent pheresis: the BioLogic-Detoxification Plasma Filtration System, ASAIO J , 1998, 44, M659-65

Lew, J.;Reichelderfer, P.;Fowler, M.;Bremer, J.;Carrol, R.;Cassol, S.;Chernoff, D.;Coombs, R.;Cronin, M.;Dickover, R.;Fiscus, S.;Herman, S.;Jackson, B.;Kornegay, J.;Kovacs, A.;McIntosh, K.;Meyer, W.;Michael, N.;Mofenson, L.;Moye, J.;Quinn, T.;Robb, M.;Vahey, M.;Weiser, B.;Yeghiazarian, T., Determinations of levels of human immunodeficiency virus type 1 RNA in plasma: reassessment of parameters affecting assay outcome, J. Clin. Microbiol. , 1998, 36, 1471-9

Lewandowski, G.;Hobbs, M.;Geller, A. I., Evidence that deficient IFN-g production is a biological basis of herpes simplex virus type-2 neurovirulence, J Neuroimmunol , 1998, 81, 66-75

Li D, Yin X, Zmuda EJ, Wolford CC, Dong X, White MF, Hai T, The repression of IRS2 gene by ATF3, a stress-inducible gene, contributes to pancreatic beta-cell apoptosis, Diabetes , 2008, 57(3), 635-44 pubmed

Li J, Baud O, Vartanian T, Volpe JJ, Rosenberg PA, Peroxynitrite generated by inducible nitric oxide synthase adn NADPH oxidase mediates microglial toxicity to oligodendrocytes., , , ,

Li J, Baud O, Vartanian T, Volpe JJ, Rosenberg PA, Peroxynitrite generated by inducible nitric oxide synthase adn NADPH oxidase mediates microglial toxicity to oligodendrocytes., National Academy of Sciences of the USA , 2005, ,

Li J, Lin JC, Wang H, Peterson JW, Furie BC, Furie B, Booth SL, Volpe JJ, Rosenberg PA., Novel role of vitamin k in preventing oxidative injury to developing oligodendrocytes and neurons, J Neurosci. , 2003 , 23(13):, 5816-26 pubmed

Li, J.; Baud, O.; Vartanian, T.; Volpe, J.J. and Rosenberg, P.A., Peroxynitrite generated by inductible nitric oxide synthase and NADPH oxidase mediates microglial toxicity to oligodendrocytes, Proceedings of the National Academy of Sciences of the USA , 2005, ,

Li, Y.H.; Lu, W.Y.; He, X.; Bu, G.J., Modulation of LRP6-mediated Wnt signaling by molecular chaperone Mesd., Febs Letters , 2006, 580, 5423-5428 pubmed

Liadaki K, Kho AT, Sanoudou D, Schienda J, Flint A, Beggs AH, Kohane IS, Kunkel L, Side population cells isolated from different tissues share transcriptome signatures and express tissue- specific markers, Exper Cell Res , 2005, 303, 360-74 pubmed

Liadaki K, Luth ES, Kunkell LM, Co-detection of GFP and dystrophin in skeletal muscle tissue sections, Biotechniques , 2007, 42(6), 699-700 pubmed

Liang OD, Mitsialis SA, Fernandez-Gonzalez A, Chang MS, Kourembanas S, Bone marrow derived mesenchymal stem cells expressing human heme oxygenase-1 (HO-1) reverse hypoxic pulmonary hypertension, Circ Res , 2008, (in press),

Lidov, H. G. W., Dystrophin in the nervous system, Brain Pathol. , 1996, 6, 63-77

Lidov, H. G.;Kunkel, L. M., Dp140: alternatively spliced isoforms in brain and kidney, Genomics , 1997, 45, 132-9

Lidov, H. G.;Kunkel, L. M., Dystrophin and Dp140 in the adult rodent kidney, Laboratory Invest , 1998, 78, 1543-51

Ligon K, Kesari S, Kitada M, Sun T, Arnett H, Alberta J, Anderson D, Stiles C, Rowitch D, Development of NG2 neural progenitor cells requires Olig gene function, Proc Natl Acad Sci U S A , 2006, 103, 7853-8 pubmed

Ligon KL, Alberta JA, Kho AT, Weiss J, Kwaan MR, Nutt CL, Louis DN, Stiles CD, Rowitch DH., The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas., J Neuropathol Exp Neurol. , 2004, 63(5), 499-509 pubmed

Ligon KL, Huillard E, Mehta S, Kesari S, Liu H, Alberta JA, Bachoo RM, Kane M, Louis DN, Depinho RA, Anderson DJ, Stiles CD, Rowitch DH, Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma, Neuron , 2007, 53(4), 503-17 pubmed

Ligon, K. L.;Echelard, Y.;Assimacopoulos, S.;Danielian, P. S.;Kaing, S.;Grove, E. A.;McMahon, A. P.;Rowitch, D. H., Loss of Emx2 function leads to ectopic expression of Wnt1 in the developing telencephalon and cortical dysplasia, Development , 2003, 130, 2275-2287

Lim J, Jin O, Bennet C, Morgan K, Wang F, Trenor C, Fleming M, Andrews N, A mutation in Sec 15I1 causes anemia in hemoglobin deficit (hbd) mice, Nature Genetics , 2005, 37, 1264-9

Lim KH, Engle EC, Demer JL, Abnormalities of the oculomotor nerve in congenital fibrosis of the extraocular muscles and congenital oculomotor palsy, Invest Ophthalmol Vis Sci , 2007, 48(4), 1601-6 pubmed

Lim M, Soul J, Hansen RM, Mayer DL, Moskowitz A, Fulton AB. , Development of acuity in children with cerebral visual impairment., Archives Ophthalmol , 2005, 123(9), 1215-1220 pubmed

Lim M, Soul JS, Hansen R, Mayer DL, Moskowitz A, Fulton A , Development of acuity in children with cerebral visual impairment, Arch Ophthalmol , 2005, 9, 1215-20 pubmed

Lim M, Soul JS, Hansen R, Mayer DL, Moskowitz A, Fulton A, Development of visual acuity in children with cerebral visual impairment, Arch Ophthalmol , 2005, 123(9), 1215-20

Lim, F.;Hartley, D.;Starr, P.;Lang, P.;Song, S.;Yu, L.;Wang, Y.;Geller, A. J., Generation of high-titer defective HSV-1 vectors using an IE2 deletion mutant and quantitative study of expression in cultured cortical cells, Biotechniques , 1996, 20, 460-470

Lim, F.;Hartley, D.;Starr, P.;Song, S.;Lang, P.;Yu, L.;Wang, Y.;Geller, A. I., Use of defective herpes-derived plasmid vectors, Recombinant Gene Expression Protocols. Methods in Molecular biology , 1997, 62, 223-232

Limperopoulos C, Bassan H, Sullivan NR, Soul JS, Robertson RL Jr, Moore M, Ringer SA, Volpe JJ, du Plessis AJ., Positive screening for autism in ex-preterm infants: prevalence and risk factors, Pediatrics , 2008, 121/ 4, 758-65

Limperopoulos C, Benson CB, Bassan H, Disalvo DN, Kinnamon DD, Moore M, Ringer SA, Volpe JJ, du Plessis AJ, Cerebellar hemorrhage in the preterm infant: ultrasonographic findings and risk factors, Pediatrics , 2005, 3, 717-24 pubmed

Limperopoulos C, Robertson RL Jr, Khwaja OS, Robson CD, Estroff JA, Barnewolt C, Levine D, Morash D, Nemes L, Zaccagnini L, du Plessis AJ, How accurately does current fetal imaging identify posterior fossa anomalies?, AJR Am J Roentgenol , 2008, 190/ 6, 1637-43

Limperopoulos C, Robertson RL, Estroff JA, Barnewolt C, Levine D, Bassan H, du Plessis AJ, Diagnosis of inferior vermian hypoplasia by fetal magnetic resonance imaging: potential pitfalls and neurodevelopmental outcome, Am J Obstet Gynecol , 2006, 194(4), 1070-6 pubmed

Limperopoulos C, Soul JS, Gauvreau K, Huppi PS, Warfield SK, Bassan H, Robertson RL, Volpe JJ, du Plessis AJ., Late gestation cerebellar growth is rapid and impeded by premature birth., Pediatrics , 2005 , 115(3), 688-95 pubmed

Limperopoulos C, Soul JS, Haidar H, Huppi PS, Basan H, Warfield SK, Robertson RL, Moore M, Akins PK, Volpe JJ, du Plessis AJ, Impaired trophic interactions between the cerebellum and the cerebrum among preterm infants, Pediatrics , 2005, 4, 844-50 pubmed

Lin H, Yamada Y, Nguyen S, Linhart H, Jackson-Grusby L, Meissner A, Meletis K, Lo G, Jaenisch R, Suppression of intestinal neoplasia by deletion of Dnmt3b, mol Cell Biol , 2006, 26, 2976-83 pubmed

Lin J.C., and Cepko, C.L., Biphasic dispersion of clones containing Purkinje cells and glia in the developing chick cerebellum. , Dev. Biol. , 1999, 211(2), 177-197 pubmed

Lin J.C., Cai L., Cepko C.L., The external granule layer of the developing chick cerebellum generates granule cells and cells of the isthmus and rostral hindbrain, Neurosci. , 2001, 21, 159-168 pubmed

Lin S-Y, Corey D, TRP channels in mechanosensation , Current Opinion in Neurobiology , 2005, 15, 350-7

Lin S-Y, Vollrath M, Hopkins N, Corey D, Pinball Wizard, a deafness and blindness gene in zebrafish, encodes an essential vesice protein at ribbon synapses, in revision at Neuron , , ,

Lin, P. T.;Gleeson, J. G.;Corbo, J. C.;Flanagan, L.;Walsh, C. A., DCAMKL1 encodes a protein kinase with homology to doublecortin that regulates microtubule polymerization, J Neurosci , 2000, 20, 9152-61 pubmed

Lin, S-y., Vollrath, M.A., Corey, D.P. and Hopkins, N. , Disruption of the zebrafish pinball wizard gene causes blindness and deafness, in revision at Neuron , , ,

Lin, Y.;Liu, A.;Zhang, S.;Ruusunen, T.;Kreidberg, J. A.;Peltoketo, H.;Drummon, I.;Vainio, S., Induction of ureter branching as a response to Wnt-2b signaling during early kidney organogenesis, Developmental Dynamics , 2001, 222, 26-39 pubmed

Linares, L. O.;Heeren, T.;Bronfman, E.;Zuckerman, B.;Augustyn, M.;Tronick, E., A mediational model for the impact of exposure to community violence on early child behavior problems, Child Dev , 2001, 72, 639-52 pubmed

Lipshultz, S. E.;Easley, K. A.;Orav, E. J.;Kaplan, S.;Starc, T. J.;Bricker, J. T.;Lai, W. W.;Moodie, D. S.;McIntosh, K.;Schluchter, M. D.;Colan, S. D., Left ventricular structure and function in children infected with human immunodeficiency virus: the prospective P2C2 HIV Multicenter Study. Pediatric Pulmonary and Cardiac Complications of Vertically Transmitted HIV Infection (P2C2 HIV) Study Group, Circulation , 1998, 97, 1246-56

Lisovsky, M.;Itoh, K.;Sokol, S. Y., Frizzled receptors activate a novel JNK-dependent pathway that may lead to apoptosis, Curr Biol , 2002, 12, 53-58

Liu F, Jenssen TK, Trimarchi J, Punzo C, Cepko CL, Ohno-Machado L, Hovig E, Kuo WP, Comparison of hybridization-based and sequencing-based gene expression technologies on biological replicates, BMC Genomics , 2007, 8, 153 pubmed

Liu j XJ, Chow KH, Clapham DE, Ren DJ, CatSper beta, a novel transmebrane protein in the CatSper channel complex, Jounal of Biological Chmistry , 2007, 282, 18945-52 pubmed

Liu K, Akula J, Falk C, Hansen R, Fulton A, The retinal vasculature and function of the neural retina in a rat model of retinopathy of prematurity, Invest Ophthalmol Vis Sci , 2006, 47(6), 2639-47 pubmed

Liu K, Akula J, Hansen R, Moskowitz A, Kleinman M, Fulton A, Development of the electroretinographic oscillatory potentials in normal and ROP rats, Invest Ophthalmol Vis Sci , 2006, 47(12), 5447-52 pubmed

Liu W, Khare SL, Liang X, Peters MA, Liu X, Cepko CL, Xiang M, All Brn3 genes can promote retinal ganglion cell differentiation in the chick., Development , 2000, 127(15), 3237-47 pubmed

Liu X, Chen C, Different Roles for AMPA and NMDA Receptors in Transmission at the Immature Retinogeniculate Synapse, J Neurophysiol , 2008, 99(2), 629-43 pubmed

Liu XZ, Ouyang XM, Xia XJ, Zheng J, Pandya A, Li F, Du LL, Welch KO, Petit C, Smith RJ, Webb BT, Yan D, Arnos KS, Corey D, Dallos P, Nance WE, Chen ZY., Prestin, a cochlear motor protein, is defective in non-syndromic hearing loss., Human Molecular Genetics , 2003, 12, 1155-1162 pubmed

Liu Y, Yang FC, Okuda T, Dong X, Zylka MJ, Chen CL, Anderson DJ, Kuner R, Ma Q, Mechanisms of compartmentalized expression of Mrg class G-protein-coupled sensory receptors, J Neurosci , 2008, 28(1), 125-32 pubmed

Liu, C.;Kato, Y.;Zhang, Z.;Do, V. M.;Yankner, B. A.;He, X., beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xenopus axis formation, PNAS USA , 1999, 96, 6273-8

Liu, C.;Y, Li;Semenov, M.;Baeg, G. H.;Han, C.;Tan, Y.;Zhang, Z.;Lin, X.;He, X., Control of beta-catenin phosphorylation-degradation by a dual-kinase mechanism, Cell , 2002, 108, 837-847

Liu, E.;Robertson, R. L.;du Plessis, a J.;Pomeroy, S. L., Basal ganglia germinoma with progressive cerebral hemiatrophy, Pediatr Neurol , 1999, 20, 312-314

Liu, Y.;Himes, B. T.;Solowska, J.;Moul, J.;Chow, S. Y.;Park, K. I.;Tessler, A.;Murray, M.;Snyder, E. Y.;Fischer, I., Intraspinal delivery of neurotrophin-3 using neural stem cells genetically modified by recombinant retrovirus, Exp Neurol , 1999, 158, 26-Sep

Liu, Z.;Holmes, G. L., Basic fibroblast growth factor-induced seizures in rats, Neurosci Lett , 1997, 233, 85-8

Liu, Z.;Holmes, G. L., Basic fibroblast growth factor is highly neuroprotective against seizure-induced long-term behavioural deficits, Neuroscience , 1997, 76, 1129-38

Liu, Z.;Stafstrom, C. E.;Sarkisian, M. R.;Yang, Y.;Hori, A.;Tandon, P.;Holmes, G. L., Seizure-induced glutamate release in mature and immature animals: an in vivo microdialysis study, Neuroreport , 1997, 8, 2019-23

Liu, Z.;Stafstrom, C. E.;Sarkisian, M.;Tandon, P.;Yang, Y.;Hori, A.;Holmes, G. L., Age-dependent effects of glutamate toxicity in the hippocampus, Brain Research , 1996, Developmental Brain Research. 97, 178-84

Liu, Z.;Yang, Y.;Silveira, D. C.;Sarkisian, M. R.;Tandon, P.;Huang, L. T.;Stafstrom, C. E.;Holmes, G. L., Consequences of recurrent seizures during early brain development, Neuroscience , 1999, 92, 1443-54

Livesey F.J., Furukawa T., Steffen M.A., Church G.M., Cepko C.L., Microarray analysis of the transcriptional network controlled by the photoreceptor homeobox gene Crx., Current Biology , 2000, 10, 301-310 pubmed

Livesey FJ, Young TL, Cepko CL., An analysis of the gene expression program of mammalian neural progenitor cells, Proc Natl Acad Sci U S A , 2004, 101, 1374-1379 pubmed

Lock, M.;Greenberg, M. E.;Lafrate, A. J.;Swigut, T.;Muench, J.;Kirchhoff, F.;Shohdy, N.;Skowronski, J., Two elements target SIV Nef to the AP-2 clathrin adaptor complex, but only one is required for the induction of CD4 endocytosis, EMBO J , 1999, 18, 2722-33

Lofqvist C, Chen J, Connor KM, Smith AC, Aderman CM, Liu N, Pintar JE, Ludwig T, Hellstrom A, Smith LE, IGFBP3 suppresses retinopathy through suppression of oxygen-induced vessel loss and promotion of vascular regrowth, Proc Natl Acad Sci U S A , 2007, 104(25):, 10589-94 pubmed

Logan D, Catanese S, Coakly R, Scharff L. , Chronic Pain in the Classroom: Teachers' Attributions About the Causes of Chronic Pain. , Journal of School Health , 2007, , 248-56 pubmed

Lois E, Smith, Retinal and Choroidal Angiogenesis, Dordrecht, The Netherlands , 2008, , 139-49

Longo, L. M.;Faugeras, O. D.;Grimson, W. E.;Keriven, R.;Kikinis, R.;Nabavi, A.;Westin, C. F., CURVES: curve evolution for vessel segmentation, Med Image Anal , 2001, 5, 195-206

Lopera, F.;Ardilla, A.;Martinez, A.;Madrigal, L.;Arango-Viana, J. C.;Lemere, C. A.;Arango-Lasprilla, J. C.;Hincapie, L.;Arcos-Burgos, M.;Ossa, J. E.;Behrens, I. M.;Norton, J.;Lendon, C.;Goate, A. M.;Ruiz-Linares, A.;Rosselli, M.;Kosik, K. S., Clinical features of early-onset Alzheimer\'s disease in a large kindred with an E280A presenilin-1 mutation, JAMA , 1997, 277(10), 793-799

Lopez, M. F.;Dikkes, P.;Zurakowski, D.;Villa-Komaroff, L., Insulin-like growth factor II affects the appearance and glycogen content of glycogen cells in the murine placenta, Endocrinology , 1996, 137, 2100-2108

Lopez, M. F.;Dikkes, P.;Zurakowski, D.;Villa-Komaroff, L.;Majzoub, J. A., Regulation of hepatic glycogen in the insulin-like growth factor II-deficient mouse, Endocrinology , 1999, 140(3), 1442-8

Lorenzo, A.;Yankner, B. A., Amyloid fibril toxicity in Alzheimer's disease and diabetes, Ann. NY Acad. Sci. , 1996, 777, 89-95

Lorenzo, A.;Yuan, M.;Zhang, Z.;Paganetti, P. A.;Sturchler-Pierrat, C.;Staufenbiel, M.;Mautino, J.;Sol Vigo, F.;Yankner, B. A., Amyloid interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer\'s disease, Nature Neurosci , 2000, 3, 460-464 pubmed

Lotery, A. J.;Jacobson, S. G.;Fishman, G. A.;Weleber, R. G.;Fulton, A. B.;Namperumalsamy, P.;Heon, E.;levin, A. V.;Grover, S.;Rosenow, J. R.;Kopp, K. K.;Sheffield, V. C.;Stone, E. M., Mutations in the CRB1 gene cause Leber congenital amaurosis, Arch Ophthalmol , 2001, 119(3), 415-420 pubmed

Louis, D. N.;Pomeroy, S. L.;Cairncross, J. G., Focus on central nervous system neoplasia, Cancer Cell , 2002, 1, 125-128 pubmed

Lu CS, Van Vactor D, Synapse specificity: Wnts keep motor axons on target, Curr Biol , 2007, 17(20), R895-8 pubmed

Lu J, Lian G, Lenkinski R, De Grand A, Vaid R, Bryce T, Stasenko M, Boskey A, Walsh C, Sheen V, Filamin B mutations cause chondrocyte precursor defects in skeletal development, Human Molecular Genetics , 2007, (in press), pubmed

Lu QR, Cai L, Rowitch D, Cepko CL, Stiles CD., Ectopic expression of Olig1 promotes oligodendrocyte formation and reduces neuronal survival in developing mouse cortex., Nat Neurosci , 2001, 4, 973-4

Lu T, Pan Y, Kao SY, Li C, Kohane I, Chan J, Yankner BA., Gene regulation and DNA damage in the ageing human brain., Nature , 2004 , 429(6994), 883-91 pubmed

Lu Y, Li Y, Herin GA, Aizenman E, Epstein PM, Rosenberg PA., Elevation of intracellular cAMP evokes activity-dependent release of adenosine in cultured rat forebrain neurons., Eur J Neurosci. , 2004 , 19(10), 2669-81 pubmed

Lu Y, Rosenberg PA, NMDA receptor-mediated extracellular adenosine accumulation is blocked by phosphatase 1/2A inhibitors, Brain Res , 2007, 1155, 116-24 pubmed

Lu, C.;Stomper, P. C.;Drislane, F. W.;Wen, P. Y.;Block, C. C.;Humphrey, C. C.;Collins, C. A.;Jolesz, F.;Talcott, J. A., Suspected spinal cord compression in breast cancer patients: A multidisciplinary risk assessment, Breast Cancer Res. Treat. , 1998, 51, 121-131

Lu, M.;Witke, W.;Kwiatkowski, D. J.;Kosik, K. S., Delayed retraction of filopodia in gelsolin null mice, J Cell Biol , 1997, 138, 1279-87

Lu, Q. R.;Cai, L.;Rowitch, D. H.;Cepko, C. L.;Stiles, C. W., Ectopic expression of Olig 1 promotes formation of oligodendrocytes and is deleterious to neuronal survival in developing mouse cortexEctopic expression of Olig1 promotes oligodendrocyte formation and reduces neuronal survival in developing mouse cortex., Nat Neurosci , 2001, 4, 973-974 pubmed

Lu, Q. R.;Mukhopadhyay, N. K.;Griffin, J. D.;Paredes, M.;Medina, M.;Kosik, K. S., Brain armadillo protein d-catenin interacts with Abl tyrosine kinase and modulates cellular morphogenesis in response to growth factors, J Neurosci Res , 2002, 67, 618-624

Lu, Q. R.;Park, J.;Noll, E;Chan, J. A.;Alberta, J.;Yuk, D.;Garcia Alzamora, M.;Louis, D. N.;Stiles, C. D;Rowitch, d H.;Black, P. M., Oligodendrocyte lineage genes (OLIG) as as molecular markers for human glial brain tumors, PNAS , 2001, 98, 10851-10856 pubmed

Lu, Q. R.;Sun, T.;Zhu, Z.;Ma, N.;Garcia, M.;Stiles, C. D.;Rowitch, D. H., Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection, Cell , 2002, 109, 75-86 pubmed

Lu, Q. R.;Yuk, D.;Alberta, J. A.;Zhu, Z.;Pawlitzky, I.;Chan, J.;McMahon, A. P.;Stiles, C. D.;Rowitch, D. R., Sonic hedgehog-regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system, Neuron , 2000, 25, 317-329 pubmed

Lu, Q.;Paredes, M.;Medina, M.;Zhou, J.;Cavallo, R.;Peifer, M.;Orecchio, L.;Kosik, K. S., d-catenin, an adhesive junction associated protein which promotes cell scattering, J. Cell Biol. , 1999, 144, 519-532

Lu, Q.;Paredes, M.;Zhang, J.;Kosik, K. S., Basal ERK activity modulates cell-cell and cell-matrix interactions, Mol. Cell. Biol. , 1998, 18, 3257-3265

Lu, Y.;Chung, H. J.;Li, Y.;Rosenberg, P. A., NMDA receptor-mediated extracellular adenosine accumulation in rat forebrain neurons in culture is associated with inhibition of adenosine kinase, Eur J Neurosci , 2003, 17(6), 1213-1222 pubmed

Luciana M, Gunnar M, Nelson C, Davis E, Donzella B, Children’s “catastrophic responses” to negative feedback on CANTAB’s ID/ED Set-Shifting Task: Relation to Indices of a Depressive temperamental Style, Cognition, Brain, and Behavior , 2005, 9, 343-61

Ludwig, D. S.;Majzoub, J. A.;Al-Zahrani, A.;Dallal, G.;Blanco, I.;Roberts, S. B., High glycemic index foods, overating, and obesity, Pediatrics , 1999, 103, 6-Jan

Luke, C. J.;Schick, C.;Tsu, C.;Whisstock, J. C.;Irving, J. A.;Bromme, D.;Juliano, L.;Shi, G. P.;Chapman, H. A.;Silverman, G. A., Simple modifications of the serpin reactive site loop converts SCCA2 into a cysteine proteinase inhibitor: A critical role for the P3\' proline in cathepsin S inhibition, Biochemistry , 2000, 39, 7081-7091 pubmed

Lukowski A, Wiebe S, Haight J, DeBoer T, Nelson C, Bauer P, Forming a Stable Memory Representation in the First Year of Life: Why Imitation is More Than Child’s Play, Developmental Science , 2005, 8, 279-98 pubmed

Luo L, Flanagan JG, Development of continuous and discrete neural maps, Neuron , 2007, 56(2), 284-300 pubmed

Luo, Z. G.;Wang, Q.;Zhou, J.;Wang, J.;Luo, Z. J.;Liu, M.;He, X.;Wynshaw-Boris, A.;Xiong, W. C.;Lu, G.;Mei, L., Regulation of AChR Clustering by Dishevelled Interacting with MuSK and PAK1, Neuron , 2002, 35, 489-505

Luth ES, Jun SJ, Wessen MK, Liadaki K, Gussoni E, Kunkel LM, Bone marrow side population cells are enriched for progenitors capable of myogenic differentiation, J Cell Sci , 2008, , pubmed

Lynch, W. P.;Sharpe, A. H.;Snyder, E. Y., Neural stem cells as engraftable packaging lines can mediate gene delivery to microglia: evidence from studying retroviral env-related neurodegeneration, J Virol , 1999, 73(8), 6841-51

Lynch, W. P.;Snyder, E. Y.;Qualtierre, L.;Portis, J. L.;Sharpe, A. H., Neither neurovirulent retroviral envelope protein nor viral particles are sufficient for the induction of acute spongiform neurodegeneration: evidence from engineered neural progenitor-derived chimeric mouse brains, J. Virol. , 1996, 70, 8896-8907

Lyons-Ruth, K.;Brushweller-Stern, N.;Harrison, A. M.;Morgan, A. C.;Nahum, J. P.;Sander, L.;Stern, D. N.;Tronick, E. Z., Implicit relational knowing: Its role in development and psychoanalytic treatment, Infant Mental Health Journal , 1998, 19, 282-289